A single, structure-searchable database of reference reactions from established sources that speeds the process of locating the right synthetic method.

RefLib contains novel organic synthetic methodologies covering functional group transformations, metal-mediated chemistry, asymmetric syntheses, and reactions abstracted from Dr. William Theilheimer's Synthetic Methods of Organic Chemistry.

RefLib covers functional group transformations, metal-mediated chemistry, asymmetric syntheses, and reactions abstracted from six Symyx databases:

• Theilheimer's Synthetic Methods of Organic Chemistry
• The Current Literature File (CLF)
• Comprehensive Heterocyclic Chemistry (CHC)
• Core
• CHIRAS
• METALYSIS

RefLib is an indispensable tool for synthetic chemists because it:

• Eliminates duplicate reactions among component databases
• Represents reagent effects on a transformation by registering these reactions as variations
• Reduces the time and cost of accessing reference reactions
• Simplifies database maintenance